Motif ID: SOX{8,9,10}.p2

Z-value: 1.003


Transcription factors associated with SOX{8,9,10}.p2:

Gene SymbolEntrez IDGene Name
SOX10 6663 SRY (sex determining region Y)-box 10
SOX8 30812 SRY (sex determining region Y)-box 8
SOX9 6662 SRY (sex determining region Y)-box 9



Activity profile for motif SOX{8,9,10}.p2.

activity profile for motif SOX{8,9,10}.p2


Sorted Z-values histogram for motif SOX{8,9,10}.p2

Sorted Z-values for motif SOX{8,9,10}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX{8,9,10}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_105511615 1.777 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr6_-_128883125 1.286 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr2_+_101680594 1.006 NM_004834
NM_145686
NM_145687
MAP4K4


mitogen-activated protein kinase kinase kinase kinase 4


chr20_-_38751289 0.901 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr1_-_117011824 0.900 NM_001007237
NM_001542
IGSF3

immunoglobulin superfamily, member 3

chr12_+_52665196 0.870 NM_017409
HOXC10
homeobox C10
chr1_-_12599934 0.751 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr10_-_123346148 0.751 NM_001144915
FGFR2
fibroblast growth factor receptor 2
chr20_-_39680405 0.731 NM_032221
CHD6
chromodomain helicase DNA binding protein 6
chr17_-_37196463 0.707 NM_002230
NM_021991
JUP

junction plakoglobin

chr11_-_27450808 0.703 NM_018490
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr19_+_12810258 0.676 NM_014975
MAST1
microtubule associated serine/threonine kinase 1
chr16_-_30841938 0.662 NCRNA00095
non-protein coding RNA 95
chr17_+_44325127 0.659 NM_001002027
NM_005175
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr6_+_132000134 0.652 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr6_-_10523424 0.652 NM_003220
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr16_+_21518633 0.643 METTL9
methyltransferase like 9
chr20_+_29656744 0.637 NM_002165
NM_181353
ID1

inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

chr8_-_29262240 0.618 NM_057158
DUSP4
dual specificity phosphatase 4
chr1_+_154855709 0.617 NM_021817
HAPLN2
hyaluronan and proteoglycan link protein 2
chr2_+_220200530 0.614 NM_005070
NM_201574
SLC4A3

solute carrier family 4, anion exchanger, member 3

chr16_+_67698943 0.611 NM_005329
HAS3
hyaluronan synthase 3
chr5_-_50714836 0.610 LOC642366
hypothetical LOC642366
chr7_+_121300394 0.608 NM_002851
PTPRZ1
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr10_-_32707549 0.600 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr1_-_155095289 0.589 NM_014215
INSRR
insulin receptor-related receptor
chr17_-_36074812 0.578 NM_152349
KRT222
keratin 222
chr12_-_23995220 0.562 SOX5
SRY (sex determining region Y)-box 5
chr14_-_89490780 0.557 NM_145231
EFCAB11
EF-hand calcium binding domain 11
chr10_-_91451102 0.555 NBAS
neuroblastoma amplified sequence
chr12_-_23995109 0.554 SOX5
SRY (sex determining region Y)-box 5
chr19_+_63482118 0.546 NM_021089
ZNF8
zinc finger protein 8
chr11_+_101488380 0.544 NM_001195045
YAP1
Yes-associated protein 1
chr20_+_3775421 0.543 NM_020746
MAVS
mitochondrial antiviral signaling protein
chr6_-_28663045 0.522 NM_052923
SCAND3
SCAN domain containing 3
chr5_+_50714996 0.512 ISL1
ISL LIM homeobox 1
chr1_-_2451543 0.507 NM_001010926
HES5
hairy and enhancer of split 5 (Drosophila)
chr1_+_64012154 0.501 NM_001083592
NM_005012
ROR1

receptor tyrosine kinase-like orphan receptor 1

chr5_-_16989290 0.487 MYO10
myosin X
chr18_-_13905534 0.483 NM_000529
MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr5_+_76047536 0.483 NM_001992
F2R
coagulation factor II (thrombin) receptor
chr15_+_38923470 0.483 NM_003710
NM_181642
SPINT1

serine peptidase inhibitor, Kunitz type 1

chr18_+_3437607 0.482 NM_173207
TGIF1
TGFB-induced factor homeobox 1
chr20_-_538909 0.480 NM_004609
TCF15
transcription factor 15 (basic helix-loop-helix)
chr19_-_60369731 0.480 NM_178837
C19orf51
chromosome 19 open reading frame 51
chr11_-_16380967 0.478 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr1_+_93686154 0.473 NM_001024948
NM_001164473
NM_017737
FNBP1L


formin binding protein 1-like


chr16_-_19440786 0.467 NM_016641
GDE1
glycerophosphodiester phosphodiesterase 1
chr17_+_16886491 0.465 NM_015134
NM_201274
MPRIP

myosin phosphatase Rho interacting protein

chr2_-_204108151 0.464 NM_203365
NM_213589
RAPH1

Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

chr1_+_158636987 0.459 NM_020335
VANGL2
vang-like 2 (van gogh, Drosophila)
chr6_+_83129641 0.456 NM_006670
TPBG
trophoblast glycoprotein
chr16_-_30705707 0.456 NM_001080417
ZNF629
zinc finger protein 629
chr14_+_23008742 0.453 NGDN
neuroguidin, EIF4E binding protein
chr14_+_36196523 0.452 NM_006194
PAX9
paired box 9
chr2_+_172658453 0.452 NM_001038493
NM_178120
DLX1

distal-less homeobox 1

chr6_-_64087806 0.451 NM_001143940
NM_016571
LGSN

lengsin, lens protein with glutamine synthetase domain

chr2_-_37752272 0.444 CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr9_-_73573121 0.443 NM_001135820
NM_013390
TMEM2

transmembrane protein 2

chr1_+_200449905 0.432 NM_001017404
LGR6
leucine-rich repeat containing G protein-coupled receptor 6
chr11_-_57173823 0.429 NM_145008
YPEL4
yippee-like 4 (Drosophila)
chr18_+_3584056 0.427 FLJ35776
hypothetical LOC649446
chr19_+_17440577 0.424 SLC27A1
solute carrier family 27 (fatty acid transporter), member 1
chr14_+_23008723 0.418 NM_001042635
NM_015514
NGDN

neuroguidin, EIF4E binding protein

chr3_-_48675321 0.417 NM_001407
CELSR3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr15_+_38923914 0.416 NM_001032367
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr6_-_42218692 0.416 NM_001164446
C6orf132
chromosome 6 open reading frame 132
chr2_+_74539039 0.414 NM_012477
WBP1
WW domain binding protein 1
chr10_+_124885556 0.409 NM_001105574
HMX3
H6 family homeobox 3
chr22_+_38652555 0.409 GRAP2
GRB2-related adaptor protein 2
chr20_+_16676997 0.408 NM_020157
OTOR
otoraplin
chr6_+_30796064 0.406 TUBB
tubulin, beta
chr11_-_101828563 0.405 NM_052932
TMEM123
transmembrane protein 123
chr20_+_20296744 0.405 NM_002196
INSM1
insulinoma-associated 1
chr10_-_115924353 0.402 NM_018017
C10orf118
chromosome 10 open reading frame 118
chr14_-_90953883 0.397 NM_001080414
CCDC88C
coiled-coil domain containing 88C
chr13_+_28900776 0.395 NM_015233
MTUS2
microtubule associated tumor suppressor candidate 2
chr3_-_150422474 0.394 NM_000096
CP
ceruloplasmin (ferroxidase)
chr5_+_50714714 0.388 NM_002202
ISL1
ISL LIM homeobox 1
chr1_-_16411690 0.387 NM_153213
ARHGEF19
Rho guanine nucleotide exchange factor (GEF) 19
chr18_+_3441589 0.385 NM_170695
NM_173210
TGIF1

TGFB-induced factor homeobox 1

chr3_+_51397731 0.383 NM_006010
MANF
mesencephalic astrocyte-derived neurotrophic factor
chr9_+_19398924 0.377 NM_001010887
ACER2
alkaline ceramidase 2
chr14_+_38714111 0.377 NM_002687
PNN
pinin, desmosome associated protein
chr6_-_80303822 0.370 NM_001122769
NM_181714
LCA5

Leber congenital amaurosis 5

chr5_+_40877053 0.370 NM_032587
CARD6
caspase recruitment domain family, member 6
chr9_-_32540818 0.369 TOPORS
topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
chr13_+_51927615 0.364 CKAP2
cytoskeleton associated protein 2
chr22_+_37193961 0.364 NM_006855
NM_016657
KDELR3

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3

chr4_+_74491272 0.361 ALB
albumin
chr9_+_22103542 0.361 CDKN2B-AS1
CDKN2B antisense RNA 1 (non-protein coding)
chr6_-_130578110 0.359 NM_152552
SAMD3
sterile alpha motif domain containing 3
chr14_+_58725104 0.355 NM_014992
DAAM1
dishevelled associated activator of morphogenesis 1
chr9_+_4782833 0.353 NM_005772
RCL1
RNA terminal phosphate cyclase-like 1
chr6_-_10523203 0.353 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr8_+_79740813 0.349 NM_016010
FAM164A
family with sequence similarity 164, member A
chr20_-_21326046 0.349 NM_033176
NKX2-4
NK2 homeobox 4
chr2_+_223244606 0.348 NM_058165
MOGAT1
monoacylglycerol O-acyltransferase 1
chr11_-_14870326 0.345 NM_024514
CYP2R1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr10_+_91451313 0.344 NM_016195
KIF20B
kinesin family member 20B
chr2_-_70329067 0.344 NM_022037
NM_022173
TIA1

TIA1 cytotoxic granule-associated RNA binding protein

chr3_-_129777618 0.341 NM_007354
C3orf27
chromosome 3 open reading frame 27
chr17_-_46298671 0.338 TOB1
transducer of ERBB2, 1
chr6_+_50894397 0.335 NM_003221
TFAP2B
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr8_+_70541631 0.334 SULF1
sulfatase 1
chr1_+_29113589 0.334 NM_001166006
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr2_+_12775814 0.332


chr8_-_22044463 0.330 NM_005144
NM_018411
HR

hairless homolog (mouse)

chr12_-_102413875 0.327 NM_198521
NM_001099336
C12orf42

chromosome 12 open reading frame 42

chr16_-_24934151 0.327 NM_001006634
NM_018054
ARHGAP17

Rho GTPase activating protein 17

chr2_-_151052391 0.326 NM_005168
RND3
Rho family GTPase 3
chr17_-_40380553 0.325 NM_001080443
KIF18B
kinesin family member 18B
chr8_+_70541412 0.324 NM_001128204
NM_015170
SULF1

sulfatase 1

chr3_+_51397756 0.323 MANF
mesencephalic astrocyte-derived neurotrophic factor
chr2_+_220017617 0.323 SPEG
SPEG complex locus
chr3_+_112743729 0.323 CD96
CD96 molecule
chr12_-_80677223 0.323 NM_003625
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr14_-_54948290 0.319 NM_014924
ATG14
ATG14 autophagy related 14 homolog (S. cerevisiae)
chr14_-_30746577 0.319


chr2_+_62787534 0.318 NM_001142614
EHBP1
EH domain binding protein 1
chr14_-_64638809 0.318 MAX
MYC associated factor X
chr14_-_19871267 0.317 NM_021178
NM_182849
CCNB1IP1

cyclin B1 interacting protein 1, E3 ubiquitin protein ligase

chr2_+_201755865 0.313 NM_001230
NM_032974
NM_032977
CASP10


caspase 10, apoptosis-related cysteine peptidase


chr2_+_17923404 0.312 NM_002252
KCNS3
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
chr5_-_16989371 0.311 NM_012334
MYO10
myosin X
chr3_+_85090721 0.310 NM_001167674
NM_001167675
CADM2

cell adhesion molecule 2

chr6_+_30796121 0.306 TUBB
tubulin, beta
chr12_-_61283474 0.303 NM_175895
C12orf61
chromosome 12 open reading frame 61
chr12_-_97812633 0.303 ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr2_-_164300758 0.302 NM_018086
FIGN
fidgetin
chr5_+_140709907 0.302 NM_018922
NM_032095
PCDHGB1

protocadherin gamma subfamily B, 1

chr4_+_119174947 0.302 NM_004784
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr3_-_107070400 0.301 NM_170662
CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr21_-_18113514 0.300 NM_001100420
NM_001100421
NM_017447
C21orf91


chromosome 21 open reading frame 91


chr14_-_30565275 0.297 NM_001083893
NM_014574
STRN3

striatin, calmodulin binding protein 3

chr3_-_88190737 0.296 NM_001008390
NM_003663
CGGBP1

CGG triplet repeat binding protein 1

chr8_+_102573837 0.293 NM_024915
GRHL2
grainyhead-like 2 (Drosophila)
chr10_-_105982052 0.292 NM_025145
WDR96
WD repeat domain 96
chr5_+_170668892 0.292 NM_021025
TLX3
T-cell leukemia homeobox 3
chr9_-_138778780 0.292 NM_203347
LCN15
lipocalin 15
chr17_-_76985538 0.290


chr2_+_190981257 0.290 NM_017694
MFSD6
major facilitator superfamily domain containing 6
chr3_+_142143329 0.288 NM_001104647
NM_018155
SLC25A36

solute carrier family 25, member 36

chr2_-_201536425 0.288 NM_006190
ORC2
origin recognition complex, subunit 2
chr14_+_62740878 0.286 NM_020663
RHOJ
ras homolog gene family, member J
chr3_+_195336625 0.285 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr3_-_49117169 0.284 NM_005051
QARS
glutaminyl-tRNA synthetase
chr16_-_52877829 0.282 IRX3
iroquois homeobox 3
chr11_-_78829342 0.281 NM_001098816
ODZ4
odz, odd Oz/ten-m homolog 4 (Drosophila)
chrX_+_152565849 0.280 DUSP9
dual specificity phosphatase 9
chr9_+_4782974 0.280 RCL1
RNA terminal phosphate cyclase-like 1
chr2_-_128285214 0.280 NM_001006622
NM_001006623
NM_018383
WDR33


WD repeat domain 33


chr3_-_101077605 0.279 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr9_+_80101810 0.279 NM_021154
NM_058179
PSAT1

phosphoserine aminotransferase 1

chr14_-_70345485 0.279 NM_033141
MAP3K9
mitogen-activated protein kinase kinase kinase 9
chr15_-_62460622 0.278 NM_001029989
NM_014736
KIAA0101

KIAA0101

chr6_+_30796123 0.278 NM_178014
TUBB
tubulin, beta
chr14_-_63830830 0.277 NM_001040275
NM_001437
ESR2

estrogen receptor 2 (ER beta)

chr7_-_92693716 0.275 NM_001039372
HEPACAM2
HEPACAM family member 2
chr10_-_99084417 0.275 NM_012083
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr19_-_6718417 0.275 NM_005490
SH2D3A
SH2 domain containing 3A
chr20_+_10363949 0.274 NM_001009608
C20orf94
chromosome 20 open reading frame 94
chr1_-_152431175 0.272 NM_152263
TPM3
tropomyosin 3
chr3_-_198509808 0.272 NM_001098424
NM_004087
DLG1

discs, large homolog 1 (Drosophila)

chr1_+_226404037 0.271 NM_020435
GJC2
gap junction protein, gamma 2, 47kDa
chr17_+_75366524 0.271 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr20_+_1132097 0.271 NM_001009612
C20orf202
chromosome 20 open reading frame 202
chr7_-_92686773 0.269 NM_198151
HEPACAM2
HEPACAM family member 2
chr21_-_33935883 0.266 NM_145858
CRYZL1
crystallin, zeta (quinone reductase)-like 1
chr1_-_197173159 0.266 LOC100131234
familial acute myelogenous leukemia related factor
chr10_-_134449467 0.265 NM_177400
NKX6-2
NK6 homeobox 2
chr5_-_88004891 0.264 LOC645323
hypothetical LOC645323
chr3_+_188131209 0.260 ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr5_-_41546384 0.260 NM_001005473
PLCXD3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr14_-_20807346 0.258 NM_001077442
NM_001077443
NM_004500
NM_031314
HNRNPC



heterogeneous nuclear ribonucleoprotein C (C1/C2)



chr6_-_2785682 0.258 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr3_-_27739201 0.256 EOMES
eomesodermin
chr1_+_85819004 0.256 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr16_+_81218142 0.256 CDH13
cadherin 13, H-cadherin (heart)
chr4_-_40211324 0.255 RBM47
RNA binding motif protein 47
chr1_+_32512298 0.254 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr11_+_22316242 0.253 NM_020346
SLC17A6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr2_-_119322228 0.252 NM_001426
EN1
engrailed homeobox 1
chr20_-_13567529 0.252 NM_017714
TASP1
taspase, threonine aspartase, 1
chr16_+_24459173 0.252 RBBP6
retinoblastoma binding protein 6
chr2_-_128285136 0.250 WDR33
WD repeat domain 33
chr6_-_116681863 0.248 NM_021648
TSPYL4
TSPY-like 4
chr4_-_101658094 0.247 NM_001159694
NM_016242
EMCN

endomucin

chr7_-_27171648 0.247 HOXA9
homeobox A9
chr6_+_122762384 0.247 NM_001135564
NM_004506
HSF2

heat shock transcription factor 2

chr20_-_33793286 0.245 RBM39
RNA binding motif protein 39
chr14_+_101346032 0.244 PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr20_-_42457717 0.244


chr15_+_38437703 0.243 NM_033510
DISP2
dispatched homolog 2 (Drosophila)
chr1_+_32992131 0.242


chr9_-_74757735 0.242 NM_000689
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr12_+_52960798 0.241 HNRNPA1L2
HNRNPA1
HNRNPA1P10
heterogeneous nuclear ribonucleoprotein A1-like 2
heterogeneous nuclear ribonucleoprotein A1
heterogeneous nuclear ribonucleoprotein A1 pseudogene 10
chr17_+_71095733 0.240 MYO15B
myosin XVB pseudogene
chr6_-_27222556 0.239 NM_080593
HIST1H2BK
histone cluster 1, H2bk
chr13_+_51927495 0.238 NM_001098525
NM_018204
CKAP2

cytoskeleton associated protein 2


Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.